According to an article at Metromix, LOST might be more inspired by Buddhist teachings than you would think.
Episodes aired in the fall revealed that the island is an experiment run by a collective known as the Dharma Initiative. Dharma is the word used to describe the collected teachings of the Buddha.
Other possible connections to Buddhism have also been seen in recent episodes:
The computer that must be tended to every 108 minutes may be a reference to the 108-bead string, or mala, that some Buddhist practitioners use during meditation.